Cannabis Safety and side effects
Medical marijuana use is generally considered safe. But different strains of marijuana have different amounts of THC. This can make dosing marijuana difficult.
Marijuana can cause:
- Dry mouth
- Dry eyes
- Paranoid thinking
- A disconnected state (dissociation)
- Increased appetite
Don't drive or operate machinery when using marijuana.
If you have a mental health condition, use marijuana with caution. Marijuana use might worsen manic symptoms in people who have bipolar disorder. If used frequently, marijuana might increase the risk of depression. Marijuana use also might worsen depression symptoms. Research suggests that marijuana use increases the risk of psychosis in people who have schizophrenia.
Smoking marijuana can affect your memory and cognitive function and cause harmful cardiovascular effects, such as high blood pressure. Long-term marijuana use can worsen respiratory conditions.
Marijuana has a central nervous system (CNS) depressant effect. As a result, marijuana use in combination with anesthesia or other drugs used during or after surgery might cause an additive effect. Don't use marijuana two weeks before planned surgery.
Possible interactions include:
- Alcohol. Marijuana use might increase the effects of alcohol.
- Anticoagulants and anti-platelet drugs, herbs and supplements. These types of drugs, herbs and supplements reduce blood clotting. Marijuana might change how the body processes them, possibly increasing the risk of bleeding.
- CNS depressants. Marijuana use in combination with CNS depressants might cause an additive sedative effect.
- Protease inhibitors. Marijuana use with use of these antiviral drugs might reduce their effectiveness.
- Selective serotonin reuptake inhibitors. Mixing marijuana with this type of antidepressant might increase the risk of mania.